Lupus - patients with autoimmune diseases have genetic problems in vitamin D metabolism, especially in their vitamin D receptor (VDR). Newly published study concludes that VDR is inversely associated with lupus activity (how much more "regulated" the VDR, less active is the disease, less inflammation). Note: the Coimbra protocol actually treats lupus and other autoimmune with high doses of vitamin D.
The expression of vitamin D receptor in peripheral blood cells is associated inversely with the activity of the disease and inflammation in patients with lupus.
(Clinical Rheumatology - 18/05/19)
"Objective: systemic lupus erythematosus (SLE) is characterized by uncontrolled production of inflammatory cytokines. The Vitamin D Receptor (VDR) has powerful anti-inflammatory activities. The aim of this study was to examine the correlation between the expression of VDR and the inflammation and activity of the disease in patients with them.
Conclusion: The expression of VDR of PBMC (peripheral blood mononuclear cells) is associated inversely with the activity of disease and inflammation in patients with them, and the regulation to the low of VDR is probably driven by inflammation."
⚠ the scientific studies published here are informative and do not replace a medical consultation.
Post Credit: Dr. Ricardo Alcantara Arteaga
#lupus #autoimmune #autoimmunedisease #SLE#systemiclupuserythematosus #cicerocoimbra #coimbraprotocol#coimbravitaminDprotocol #vitaminD